Open Access Original Research Article

Mutational Screening of the Negative Regulatory Region of Astrocyte Elevated Gene -1 Promoter in Hepatocellular Carcinoma Patients

Naghmeh Gholipour, Fatemeh Akbarian, Hamideh Khajeh, Sajjad Ghahhari, Nader Mansour Samaei

Journal of Scientific Research and Reports, Page 1-7
DOI: 10.9734/JSRR/2018/10085

Objective: This study is aimed to assess the correlation between negative regulatory region of AEG-1 promoter and genetic susceptibility to hepatocellular carcinoma in Iranian population.

Methods: The negative regulatory region of human AEG-1 promoter was explored in 50 Iranian HCC patients. The PCR-sequencing method was used for investigating AEG-1 promoter polymorphisms.

Results: This analysis did not reveal the presence of any deletions, insertions, or mutations in this region ofAEG-1 promoter.

Conclusion: Mutations in the negative regulatory region of AEG-1 promoter have no  significant relevance with hepatocellular carcinoma. Nevertheless, to our knowledge, this is the first study to investigate the mutations of the negative regulatory region of AEG-1 promoter in HCC patient. The role of AEG-1 promoter played in HCC needs to be further studied.

Open Access Original Research Article

Price Growth Rates, Co–integration and Price Leadership among Local Rice Market in the Six Geopolitical Zones of Nigeria

Y. E. Ajibade, M. O. Adetunji

Journal of Scientific Research and Reports, Page 1-17
DOI: 10.9734/JSRR/2018/15660

The study of market integration is important in determining the co movement of prices and the transmission of price signals and the information across spatially separated markets. This study describes growth rates in retail prices, examines long- run price equilibrium in local rice markets, determines markets that exhibit leadership position in price formation and transmission of spatial separated markets integration of the different pairs of markets in Nigeria for both local rice varieties and imported rice varieties. Examining the extent of interregional market integration, both spatial and across marketing stages will provide insights on the speed of trader responses in moving this vital commodity from surplus to deficit areas, especially in the face of high demand.

The data used for the analysis were collected from National Bureau of Statistics, Abuja, from January 2001 to December 2010 (120 months) per state. Eighteen spatially separated (urban) markets across six geopolitical zones in Nigeria were selected based on their development.  Augmented Dickey Fuller (ADF), Johansen Co integration technique, Granger Causality test and Vector Error Correction Model (VECM) were the analytical techniques employed.

The results of the local rice markets growth rates were highest in Bayelsa (86.15%) in 2003, followed by Lagos (72.01%) in 2005 and Bauchi (45.83%) in 2007. The empirical results revealed that price series variables became stationary after first differences. The results of Johansen Co- integration analysis revealed that 71.90% of the local rice markets showed long- run price equilibrium despite the divergence in prices. The results of Johansen multiple co integration also affirmed the co integration results among local rice markets. The results of Granger causality tests were both uni- directional and bi- directional, indicating the markets that show leadership position in price formation and transmission from one market to the other. The results of VECM revealed moderate short-run price equilibrium in the local rice markets.

In conclusion, the price signal were transmitted across spatially separated markets for locally planted rice, thus indicating integration of local rice markets across the six geopolitical zones in Nigeria. Therefore, adequate investment in local rice varieties will remove the drain in the nation’s foreign exchange.

Open Access Original Research Article

Impact of SERVQUAL and Interaction Quality on Customer Satisfaction and Delight in Transportation Services

Afaq Ahmed Khan, Naqash Ahmad Khan Tareen, Saneela Jadoon

Journal of Scientific Research and Reports, Page 1-11
DOI: 10.9734/JSRR/2018/25280

The study is carried out in order to evaluate the relationship between the constraints that influence Customer Delight and Service Quality, for which Customer Satisfaction acts as mediator and Interaction Quality playing moderating role between SERVQUAL and Customer Satisfaction. For the purpose of data collection and analysis questionnaires were dispersed through convenience sampling technique, obtaining 83.33% response rate and, processed by running several statistical tests to find out the relevant data outcomes. There is an indication of positive results as entries were evaluated, which specify that there is direct relation between the variables. Study focuses on the by-road transportation services excluding cabs or for a single person’s hiring of private vehicle. Hence, limited to provision of public travelling services within the city and also across the city. Research work will fill the area where the customer delight and satisfaction needs to be the prior by enhancing service interaction quality and service quality. And will serve this field as a new contribution and positive outcomes to this sector.

Open Access Original Research Article

Effect of Communication Channels on the Use of Tree Crops Development Units’ Services among Cocoa Farmers in Oyo State, Nigeria

J. O. Oladeji, O. A. Abimbola, A. O. Ademola, T. O. Adedeji

Journal of Scientific Research and Reports, Page 1-10
DOI: 10.9734/JSRR/2018/7810

Use of cocoa rehabilitation innovations can only be ensured if information about it is effectively communicated to cocoa farmers. This study therefore was to determine the effect of communication channels on the use of Tree Crops Development Units’ (TCDU) services among cocoa farmers in Oyo State. The population of the study included all cocoa farmers who registered with the TCDU in Oyo State. Proportionate and simple random samplings were used to select Local Government Areas and 144 respondents for the study. Data was summarized using descriptive statistics and analysed using inferential statistics. Result of analysis indicated that farmers source most of TCDU’s information from farmers’ group and radio. Many of the farmers were not well informed about TCDU because they did not expose themselves to available communication channels. Majority of the cocoa farmers had a favourable perception of the communication channels employed by the Unit and often use TCDU services. Many of the farmers already had another means of sourcing inputs. Discontinued use of the Unit’s services was due to the Unit’s inadequacy, untimely reports and lack of dynamism. The higher the use of communication channels the lower the use of TCDU services. Likewise, the higher the farmers’ perception of the communication channels, the lower the use of the services. It is recommended that agricultural programmes should be dynamic enough to keep farmers’ interest. Also, enabling social, economic, and infrastructural environment should be created to facilitate the use of innovations.

Open Access Original Research Article

Catalytic Transformations of 4-tert-Butylphenol in Hydrogen Peroxide Solutions in the Presence of Titanium Oxide Compounds and Titanosilicates

R. R. Talipova, R. U. Kharrasov, A. D. Badikova, B. I. Kutepov

Journal of Scientific Research and Reports, Page 1-11
DOI: 10.9734/JSRR/2018/19723

The selective oxidation of 4-tert-butylphenol by H2O2 solutions in the presence of titanosilicate catalysts could become a promising alternative for the 4-tert-butylcatechol production. In this study the catalytic transformations of 4-tert-butylphenol in hydrogen peroxide solutions were investigated in the presence of the titanium oxide samples of different phase composition and the samples of crystalline and amorphous titanosilicates. The primary product of the 4-tert-butylphenol conversion in the presence of both hydrated and amorphous TiO2 forms was 4-tert-butylphenol ether. The maximum selectivity value of the latter was 80 mol.%. The 4-tert-butylcatechol formation selectivity reached its maximum in the presence of the anatase TiOform but did not exceed 20 mol.%. The TS-1 microporous crystalline titanosilicate was shown to ehxibit low activity in the 4-tert-butylphenol transformation due to the steric limitations on the diffusion of the substrate molecules towards catalytic active centers. Mesoporous amorphous titanosilicates were more selective in the 4-tert-butylcatechol formation than the titanium oxide compound samples. It was found that the mesoporous titanosilicate content in the reaction mix, temperature and the experiment duration affected both the 4-tert-butylphenol conversion and the 4-tert-butylcatechol formation selectivity. The maximum 53 mol.% formation selectivity value of the 4-tert-butylcatechol was shown to occur over the amorphous mesoporous titanosilicate containing 1.9 wt.% of Ti, the 4-tert-butylphenol conversion value being equal to 42 mol.%.