Emerging Importance of Viral Transport Media in High-Throughput Sequencing Fidelity for Genomic Analysis
Nisha Beniwal
Indian Council of Medical Research – Regional Medical Research Centre (ICMR-RMRC), Port Blair, Andaman and Nicobar Islands, India.
Baljeet Singh Saharan
*
Department of Microbiology, CCS Haryana Agricultural University, Hisar-125004, India.
*Author to whom correspondence should be addressed.
Abstract
The impact of Viral Transport Media (VTM) components on the efficacy and accuracy of high-throughput Next-Generation Sequencing (NGS) techniques is a subject of paramount importance in the field of viral genomics and diagnostics. VTMs play a pivotal role in preserving viral samples, and their composition can profoundly influence the quality and reliability of NGS results. This study explores the intricate relationship between VTM components and NGS outcomes, with a focus on optimizing diagnostic precision and the efficiency of NGS in viral genomics. Through comprehensive investigation, this research sheds light on the critical implications of VTM composition for enhancing viral genomic analysis, streamlining diagnostic processes, and bolstering public health responses. The findings have far-reaching consequences, including the potential for personalized medicine, rapid detection of emerging viral threats, and the improvement of public health surveillance. Standardized protocols and ongoing technological advancements are essential in harnessing the full potential of NGS for genomics and metagenomics, marking a significant step toward more effective viral disease management and outbreak response.
Keywords: Viral transport media, next-generation sequencing, metagenomics, sequencing accuracy, NGS library preparation
How to Cite
References
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