Gut Uptake, Brain and Behaviour
Tveiten D. Bioeng
The Pepide Research Unit, Lab1, Oslo No-0275, Oslo, Norway.
K. L. Reichelt *
The Pepide Research Unit, Lab1, Oslo No-0275, Oslo, Norway and Kleve 4541, Oslo University, Blindern No-0139, Oslo, Norway.
*Author to whom correspondence should be addressed.
Abstract
Aims: To document the evidence for a gut uptake to brain axis. The many hormones, many of them peptides and shared by the intestines and the brain, will not be included in this survey.
Methods: Systematic looking through journal publications by means of Pub med and collected information and authors research since 1978.
Results: Food-protein antibodies, food-protein derived peptides and direct physiological evidence point to considerable effect of the digestive system on behavior and mood. Removal of specific proteins from diet ameliorates the clinical condition.
Conclusion: Uptake from the gut of various substances has effect on behaviour.
Keywords: Gut uptake, antibodies, peptides, behaviour